A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2
Wide-spread outbreaks of pathogens require high intensity testing to manage. Here, the authors present C19-SPAR-Seq, a scalable and automated platform to analyse tens of thousands of SARS-CoV-2 patient samples in a single run.
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Nature Publishing Group
2021-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-21653-y |
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doaj-ac044901fa7a4d629bfedd519a0399c22021-03-11T11:33:53ZengNature Publishing GroupNature Communications2041-17232021-03-0112111010.1038/s41467-021-21653-yA multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2Marie-Ming Aynaud0J. Javier Hernandez1Seda Barutcu2Ulrich Braunschweig3Kin Chan4Joel D. Pearson5Daniel Trcka6Suzanna L. Prosser7Jaeyoun Kim8Miriam Barrios-Rodiles9Mark Jen10Siyuan Song11Jess Shen12Christine Bruce13Bryn Hazlett14Susan Poutanen15Liliana Attisano16Rod Bremner17Benjamin J. Blencowe18Tony Mazzulli19Hong Han20Laurence Pelletier21Jeffrey L. Wrana22Lunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalDonnelly Centre for Cellular and Biomolecular Research, University of TorontoLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalDonnelly Centre for Cellular and Biomolecular Research, University of TorontoLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalDepartment of Microbiology, Mount Sinai Hospital/University Health NetworkDepartment of Microbiology, Mount Sinai Hospital/University Health NetworkDepartment of Microbiology, Mount Sinai Hospital/University Health NetworkDonnelly Centre for Cellular and Biomolecular Research, University of TorontoLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalDonnelly Centre for Cellular and Biomolecular Research, University of TorontoDepartment of Microbiology, Mount Sinai Hospital/University Health NetworkDonnelly Centre for Cellular and Biomolecular Research, University of TorontoLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalLunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalWide-spread outbreaks of pathogens require high intensity testing to manage. Here, the authors present C19-SPAR-Seq, a scalable and automated platform to analyse tens of thousands of SARS-CoV-2 patient samples in a single run.https://doi.org/10.1038/s41467-021-21653-y |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Marie-Ming Aynaud J. Javier Hernandez Seda Barutcu Ulrich Braunschweig Kin Chan Joel D. Pearson Daniel Trcka Suzanna L. Prosser Jaeyoun Kim Miriam Barrios-Rodiles Mark Jen Siyuan Song Jess Shen Christine Bruce Bryn Hazlett Susan Poutanen Liliana Attisano Rod Bremner Benjamin J. Blencowe Tony Mazzulli Hong Han Laurence Pelletier Jeffrey L. Wrana |
| spellingShingle |
Marie-Ming Aynaud J. Javier Hernandez Seda Barutcu Ulrich Braunschweig Kin Chan Joel D. Pearson Daniel Trcka Suzanna L. Prosser Jaeyoun Kim Miriam Barrios-Rodiles Mark Jen Siyuan Song Jess Shen Christine Bruce Bryn Hazlett Susan Poutanen Liliana Attisano Rod Bremner Benjamin J. Blencowe Tony Mazzulli Hong Han Laurence Pelletier Jeffrey L. Wrana A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2 Nature Communications |
| author_facet |
Marie-Ming Aynaud J. Javier Hernandez Seda Barutcu Ulrich Braunschweig Kin Chan Joel D. Pearson Daniel Trcka Suzanna L. Prosser Jaeyoun Kim Miriam Barrios-Rodiles Mark Jen Siyuan Song Jess Shen Christine Bruce Bryn Hazlett Susan Poutanen Liliana Attisano Rod Bremner Benjamin J. Blencowe Tony Mazzulli Hong Han Laurence Pelletier Jeffrey L. Wrana |
| author_sort |
Marie-Ming Aynaud |
| title |
A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2 |
| title_short |
A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2 |
| title_full |
A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2 |
| title_fullStr |
A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2 |
| title_full_unstemmed |
A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2 |
| title_sort |
multiplexed, next generation sequencing platform for high-throughput detection of sars-cov-2 |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2021-03-01 |
| description |
Wide-spread outbreaks of pathogens require high intensity testing to manage. Here, the authors present C19-SPAR-Seq, a scalable and automated platform to analyse tens of thousands of SARS-CoV-2 patient samples in a single run. |
| url |
https://doi.org/10.1038/s41467-021-21653-y |
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