Microencapsulated Tuna Oil Results in Higher Absorption of DHA in Toddlers
Docosahexaenoic acid (DHA) is an essential component for brain and visual acuity development during foetal and early postnatal life. A newly released directive under the European Commission stipulates DHA as a mandatory ingredient in infant formula. This poses challenges to manufacturers in preservi...
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doaj-ac2340125396448b8a30de1e756aaa7c2020-11-25T02:05:45ZengMDPI AGNutrients2072-66432020-01-0112124810.3390/nu12010248nu12010248Microencapsulated Tuna Oil Results in Higher Absorption of DHA in ToddlersSamaneh Ghasemi Fard0Su Peng Loh1Giovanni M. Turchini2Bo Wang3Glenn Elliott4Andrew J. Sinclair5Nu-Mega Ingredients Pty Ltd., Brisbane, QLD 4000, AustraliaDepartment of Nutrition & Dietetics, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Serdang 43300, Selangor, MalaysiaSchool of Life and Environmental Sciences, Deakin University, Geelong, VIC 3220, AustraliaSchool of Behavioural and Health Science, Australian Catholic University, Sydney, NSW 2000, AustraliaNu-Mega Ingredients Pty Ltd., Brisbane, QLD 4000, AustraliaDepartment of Nutrition, Dietetics and Food, Monash University, Clayton, Melbourne, VIC 3168, AustraliaDocosahexaenoic acid (DHA) is an essential component for brain and visual acuity development during foetal and early postnatal life. A newly released directive under the European Commission stipulates DHA as a mandatory ingredient in infant formula. This poses challenges to manufacturers in preserving the stability and bioavailability of DHA at levels akin to human breast milk. The aims of this study were (a) to investigate the bioavailability of microencapsulated omega-3 DHA formulations in healthy toddlers compared with high DHA fish oil for a one-month period and (b) to assess the effect of DHA supplementation on children’s sleep and cry patterns. Sixty toddlers were randomly allocated to four groups: 1. unfortified formula, 2. unfortified formula plus high DHA tuna oil, 3. fortified formula with dairy-based microencapsulated high DHA tuna oil powder, and 4. fortified formula with allergenic-free microencapsulated high DHA tuna oil powder. Bioavailability was assessed from both blood and faecal fatty acid levels. The results showed an enhanced bioavailability with significantly greater concentrations of blood DHA levels in formulas with microencapsulated powders. There were no significant effects of treatment on sleep and cry patterns. Application and delivery of microencapsulated DHA tuna oil powder in toddlers’ formula provided better bioavailability of the active DHA.https://www.mdpi.com/2072-6643/12/1/248bioavailabilitymicroencapsulationtuna oilomega-3dhatoddlers |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Samaneh Ghasemi Fard Su Peng Loh Giovanni M. Turchini Bo Wang Glenn Elliott Andrew J. Sinclair |
spellingShingle |
Samaneh Ghasemi Fard Su Peng Loh Giovanni M. Turchini Bo Wang Glenn Elliott Andrew J. Sinclair Microencapsulated Tuna Oil Results in Higher Absorption of DHA in Toddlers Nutrients bioavailability microencapsulation tuna oil omega-3 dha toddlers |
author_facet |
Samaneh Ghasemi Fard Su Peng Loh Giovanni M. Turchini Bo Wang Glenn Elliott Andrew J. Sinclair |
author_sort |
Samaneh Ghasemi Fard |
title |
Microencapsulated Tuna Oil Results in Higher Absorption of DHA in Toddlers |
title_short |
Microencapsulated Tuna Oil Results in Higher Absorption of DHA in Toddlers |
title_full |
Microencapsulated Tuna Oil Results in Higher Absorption of DHA in Toddlers |
title_fullStr |
Microencapsulated Tuna Oil Results in Higher Absorption of DHA in Toddlers |
title_full_unstemmed |
Microencapsulated Tuna Oil Results in Higher Absorption of DHA in Toddlers |
title_sort |
microencapsulated tuna oil results in higher absorption of dha in toddlers |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2020-01-01 |
description |
Docosahexaenoic acid (DHA) is an essential component for brain and visual acuity development during foetal and early postnatal life. A newly released directive under the European Commission stipulates DHA as a mandatory ingredient in infant formula. This poses challenges to manufacturers in preserving the stability and bioavailability of DHA at levels akin to human breast milk. The aims of this study were (a) to investigate the bioavailability of microencapsulated omega-3 DHA formulations in healthy toddlers compared with high DHA fish oil for a one-month period and (b) to assess the effect of DHA supplementation on children’s sleep and cry patterns. Sixty toddlers were randomly allocated to four groups: 1. unfortified formula, 2. unfortified formula plus high DHA tuna oil, 3. fortified formula with dairy-based microencapsulated high DHA tuna oil powder, and 4. fortified formula with allergenic-free microencapsulated high DHA tuna oil powder. Bioavailability was assessed from both blood and faecal fatty acid levels. The results showed an enhanced bioavailability with significantly greater concentrations of blood DHA levels in formulas with microencapsulated powders. There were no significant effects of treatment on sleep and cry patterns. Application and delivery of microencapsulated DHA tuna oil powder in toddlers’ formula provided better bioavailability of the active DHA. |
topic |
bioavailability microencapsulation tuna oil omega-3 dha toddlers |
url |
https://www.mdpi.com/2072-6643/12/1/248 |
work_keys_str_mv |
AT samanehghasemifard microencapsulatedtunaoilresultsinhigherabsorptionofdhaintoddlers AT supengloh microencapsulatedtunaoilresultsinhigherabsorptionofdhaintoddlers AT giovannimturchini microencapsulatedtunaoilresultsinhigherabsorptionofdhaintoddlers AT bowang microencapsulatedtunaoilresultsinhigherabsorptionofdhaintoddlers AT glennelliott microencapsulatedtunaoilresultsinhigherabsorptionofdhaintoddlers AT andrewjsinclair microencapsulatedtunaoilresultsinhigherabsorptionofdhaintoddlers |
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