Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus
Classical swine fever virus (CSFV) causes an economically important and highly contagious disease of pigs, leading to economic losses around the world. Attenuated live vaccines with CSFV antigens have played an important role in the prevention and control of the disease. Porcine kidney 15 (PK15) cel...
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Online Access: | https://doi.org/10.2478/jvetres-2020-0020 |
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doaj-ac4316986c96497d89dddc3238b5caba2021-09-06T19:41:50ZengSciendoJournal of Veterinary Research2450-86082020-03-0164191410.2478/jvetres-2020-0020jvetres-2020-0020Cloning and identification of PK15 cells for enhanced replication of classical swine fever virusYin Mei0Hu Dongfang1Li Peng2Kong Lingyun3Ning Hongmei4Yue Feng5Jiang Jinqing6Wang Xuannian7College of Animal Science and Technology, Henan Institute of Science and Technology, Xinxiang, Henan, 453003, ChinaCollege of Animal Science and Technology, Henan Institute of Science and Technology, Xinxiang, Henan, 453003, ChinaCollege of Life Science and Technology, Xinxiang University, Xinxiang, Henan, 453003, ChinaXinxiangxian Agriculture and Animal Husbandry Bureau (Xinxiangxian Forestry Bureau), Xinxiang, Henan, 453700, ChinaCollege of Animal Science and Technology, Henan Institute of Science and Technology, Xinxiang, Henan, 453003, ChinaCollege of Life Science and Technology, Xinxiang University, Xinxiang, Henan, 453003, ChinaCollege of Animal Science and Technology, Henan Institute of Science and Technology, Xinxiang, Henan, 453003, ChinaCollege of Life Science and Technology, Xinxiang University, Xinxiang, Henan, 453003, ChinaClassical swine fever virus (CSFV) causes an economically important and highly contagious disease of pigs, leading to economic losses around the world. Attenuated live vaccines with CSFV antigens have played an important role in the prevention and control of the disease. Porcine kidney 15 (PK15) cells have been widely used for the propagation of CSFV, but this cell line is not efficient or homogeneously susceptible to viral infection.https://doi.org/10.2478/jvetres-2020-0020classical swine fever viruspk15high-permissive cellscell cloningvaccine production |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yin Mei Hu Dongfang Li Peng Kong Lingyun Ning Hongmei Yue Feng Jiang Jinqing Wang Xuannian |
spellingShingle |
Yin Mei Hu Dongfang Li Peng Kong Lingyun Ning Hongmei Yue Feng Jiang Jinqing Wang Xuannian Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus Journal of Veterinary Research classical swine fever virus pk15 high-permissive cells cell cloning vaccine production |
author_facet |
Yin Mei Hu Dongfang Li Peng Kong Lingyun Ning Hongmei Yue Feng Jiang Jinqing Wang Xuannian |
author_sort |
Yin Mei |
title |
Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus |
title_short |
Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus |
title_full |
Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus |
title_fullStr |
Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus |
title_full_unstemmed |
Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus |
title_sort |
cloning and identification of pk15 cells for enhanced replication of classical swine fever virus |
publisher |
Sciendo |
series |
Journal of Veterinary Research |
issn |
2450-8608 |
publishDate |
2020-03-01 |
description |
Classical swine fever virus (CSFV) causes an economically important and highly contagious disease of pigs, leading to economic losses around the world. Attenuated live vaccines with CSFV antigens have played an important role in the prevention and control of the disease. Porcine kidney 15 (PK15) cells have been widely used for the propagation of CSFV, but this cell line is not efficient or homogeneously susceptible to viral infection. |
topic |
classical swine fever virus pk15 high-permissive cells cell cloning vaccine production |
url |
https://doi.org/10.2478/jvetres-2020-0020 |
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