Pretreatment with a Heat-Killed Probiotic Modulates the NLRP3 Inflammasome and Attenuates Colitis-Associated Colorectal Cancer in Mice

Pretreatment with a Heat-Killed Probiotic Modulates the NLRP3 Inflammasome and Attenuates Colitis-Associated Colorectal Cancer in Mice

Colorectal cancer (CRC) is one of the most common malignancies worldwide. Inflammation contributes to cancer development and inflammatory bowel disease is an important risk factor for CRC. The aim of this study is to assess whether a widely used probiotic <i>Enterococcus faecalis</i> can...

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Bibliographic Details
Main Authors: I-Che Chung, Chun-Nan OuYang, Sheng-Ning Yuan, Hsin-Chung Lin, Kuo-Yang Huang, Pao-Shu Wu, Chia-Yuan Liu, Kuen-Jou Tsai, Lai-Keng Loi, Yu-Jen Chen, An-Ko Chung, David M. Ojcius, Yu-Sun Chang, Lih-Chyang Chen
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Nutrients
Subjects:
probiotic
NLRP3
inflammasome
colitis
cancer
Online Access:https://www.mdpi.com/2072-6643/11/3/516

Internet

https://www.mdpi.com/2072-6643/11/3/516

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