The Proapoptotic Effect of Formononetin in Human Osteosarcoma Cells: Involvement of Inactivation of ERK and Akt Pathways

The Proapoptotic Effect of Formononetin in Human Osteosarcoma Cells: Involvement of Inactivation of ERK and Akt Pathways

Background: Previous studies have shown that some phytoestrogens inhibits proliferation and induces apoptosis in estrogen-dependent cancers via estrogen receptor (ER)-mediated signaling pathway. In view of the expression of ER in human osteosarcoma cells, the purpose of this study is to investigate...

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Bibliographic Details
Main Authors: Yun Liu, JinJie He, XiaoMing Chen, Jian Li, MaoRong Shen, WenJun Yu, Yuan Yang, ZengMing Xiao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Osteosarcoma
Apoptosis
MAPK
PI3K/Akt
Calycosin
Formononetin
Online Access:http://www.karger.com/Article/FullText/363029

Internet

http://www.karger.com/Article/FullText/363029

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