Mitochondrial Dysfunction, Oxidative Stress and Neuroinflammation in Neurodegeneration with Brain Iron Accumulation (NBIA)

Mitochondrial Dysfunction, Oxidative Stress and Neuroinflammation in Neurodegeneration with Brain Iron Accumulation (NBIA)

The syndromes of neurodegeneration with brain iron accumulation (NBIA) encompass a group of invalidating and progressive rare diseases that share the abnormal accumulation of iron in the basal ganglia. The onset of NBIA disorders ranges from infancy to adulthood. Main clinical signs are related to e...

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Bibliographic Details
Main Authors: Isabel Hinarejos, Candela Machuca-Arellano, Paula Sancho, Carmen Espinós
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Antioxidants
Subjects:
neurodegenerative disorder
brain iron accumulation
rare disease
mitochondrial dysfunction
oxidative stress
neuroinflammation
Online Access:https://www.mdpi.com/2076-3921/9/10/1020

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