Ubiquitin specific peptidase Usp53 regulates osteoblast versus adipocyte lineage commitment

Abstract We have previously shown that parathyroid hormone (PTH) induces the phosphorylation of the DNA-binding protein Nascent polypeptide associated complex And Coregulator alpha (NACA), leading to nuclear translocation of NACA and activation of target genes. Using ChIP-Seq against NACA in paralle...

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Bibliographic Details
Main Authors: Hadla Hariri, William N. Addison, René St-Arnaud
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87608-x