Metabolic reprogramming of Salmonella infected macrophages and its modulation by iron availability and the mTOR pathway

Metabolic reprogramming of Salmonella infected macrophages and its modulation by iron availability and the mTOR pathway

Iron is an essential nutrient for immune cells and microbes, therefore the control of its homeostasis plays a decisive role for infections. Moreover, iron affects metabolic pathways by modulating the translational expression of the key tricarboxylic acid cycle (TCA) enzyme mitochondrial aconitase an...

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Bibliographic Details
Main Authors: Julia Telser, Chiara Volani, Richard Hilbe, Markus Seifert, Natascha Brigo, Giuseppe Paglia, Günter Weiss
Format: Article
Language:English
Published: Shared Science Publishers OG 2019-11-01
Series:Microbial Cell
Subjects:
macrophage
salmonella
krebs cycle
iron
mtor
glycolysis
Online Access:http://microbialcell.com/researcharticles/2019a-telser-microbial-cell/

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