Impact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus

Impact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus

Invariant natural killer T (iNKT) cells represent a subclass of T cells possessing a restricted repertoire of T cell receptors enabling them to recognize lipid derived ligands. iNKT cells are continuously generated in thymus and differentiate into three main subpopulations: iNKT1, iNKT2, and iNKT17...

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Bibliographic Details
Main Authors: Georgia Papadogianni, Inga Ravens, Oliver Dittrich-Breiholz, Günter Bernhardt, Hristo Georgiev
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
invariant natural killer T cells
thymus
aging
transcriptome
IL2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.575764/full

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