A Human Pluripotent Stem Cell Model of Facioscapulohumeral Muscular Dystrophy‐Affected Skeletal Muscles

A Human Pluripotent Stem Cell Model of Facioscapulohumeral Muscular Dystrophy‐Affected Skeletal Muscles

Facioscapulohumeral muscular dystrophy (FSHD) represents a major unmet clinical need arising from the progressive weakness and atrophy of skeletal muscles. The dearth of adequate experimental models has severely hampered our understanding of the disease. To date, no treatment is available for FSHD....

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Bibliographic Details
Main Authors: Leslie Caron, Devaki Kher, Kian Leong Lee, Robert McKernan, Biljana Dumevska, Alejandro Hidalgo, Jia Li, Henry Yang, Heather Main, Giulia Ferri, Lisa M. Petek, Lorenz Poellinger, Daniel G. Miller, Davide Gabellini, Uli Schmidt
Format: Article
Language:English
Published: Wiley 2016-09-01
Series:Stem Cells Translational Medicine
Subjects:
Embryonic stem cells
Muscular dystrophy
Pluripotent stem cells
Skeletal muscle
Induced pluripotent stem cells
Online Access:https://doi.org/10.5966/sctm.2015-0224

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