Ethyl Acetate Fraction of Aqueous Extract of <i>Lentinula edodes</i> Inhibits Osteoclastogenesis by Suppressing NFATc1 Expression

Bone tissue is continuously remodeled by the coordinated action of osteoclasts and osteoblasts. Nuclear factor-activated T cells c1 (NFATc1) is a well-known transcription factor for osteoclastogenesis and transcriptionally activated by the c-Fos and nuclear factor-kappa B (NF-&#954;B) signaling...

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Bibliographic Details
Main Authors: Hyerim Lee, Kyubin Lee, Sheunghun Lee, Jisu Lee, Won Tae Jeong, Heung Bin Lim, Tae Kyung Hyun, Sun-Ju Yi, Kyunghwan Kim
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/4/1347