Predictive validity of PRISMA-7 as a screening instrument for frailty in a hospital setting

Objectives Frailty is a major clinical geriatric syndrome associated with serious adverse events including functional disability, falls, hospitalisation, increased morbidity and mortality. The aim of this study was to study the associations between frailty defined as Program of Research to Integrate...

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Main Authors: Katja Kemp Jacobsen, Maurice A Lembeck, Sarah Hoffmann, Amalie Wiben, Marie Kruse, Ellen Astrid Holm
Format: Article
Language:English
Published: BMJ Publishing Group 2020-10-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/10/e038768.full
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spelling doaj-accfe23759954627aab36237d5ac4e8a2021-05-06T09:37:07ZengBMJ Publishing GroupBMJ Open2044-60552020-10-01101010.1136/bmjopen-2020-038768Predictive validity of PRISMA-7 as a screening instrument for frailty in a hospital settingKatja Kemp Jacobsen0Maurice A Lembeck1Sarah Hoffmann2Amalie Wiben3Marie Kruse4Ellen Astrid Holm5Department of Technology, Faculty of Health and Technology, University College Copenhagen, Kobenhavn, Hovedstaden, DenmarkMedical Department, Nykøbing F Sygehus, Nykøbing, Sjaelland, DenmarkMedical Department, Nykøbing F Sygehus, Nykøbing, Sjaelland, DenmarkDanish Centre for Health Economics, University of Southern Denmark, Odense, Syddanmark, DenmarkDanish Centre for Health Economics, University of Southern Denmark, Odense, Syddanmark, DenmarkMedical Department, Nykøbing F Sygehus, Nykøbing, Sjaelland, DenmarkObjectives Frailty is a major clinical geriatric syndrome associated with serious adverse events including functional disability, falls, hospitalisation, increased morbidity and mortality. The aim of this study was to study the associations between frailty defined as Program of Research to Integrate Services for the Maintenance of Autonomy (PRISMA-7) score ≥3 and use of healthcare resources in hospital and in the municipality as well as association between frailty and mortality.Design Register-based retrospective study.Setting The target population consists of patients aged 75 years or above who, during hospital stay, were assessed by a physiotherapist, and at discharge from hospital were prescribed further physical training in the community.Participants 973 individuals aged 75+ years were included.Outcome measures We examined associations between frailty and use of healthcare resources in hospital and in the municipality as well as the association between frailty and mortality.Results 973 individuals aged 75+ years were included. Of these, 63.9% had a PRISMA-7 score ≥3 and were thus defined as frail. Frail individuals were older compared with non-frail with mean ages of 84.6 and 80.4 years, respectively, p>0.001. Age and gender-adjusted mortality after 1 year was higher among the frail (OR 2.46, 95% CI 1.53 to 3.97). Use of healthcare services in the municipality as well as hospital admissions was significantly higher among frail individuals.Conclusions Based on these findings we consider PRISMA-7 to be useful in an in-hospital setting as a screening tool to identify frail elderly patients who may profit from further geriatric assessment during hospital stay.Trial registration number ID REG-070-2017.https://bmjopen.bmj.com/content/10/10/e038768.full
collection DOAJ
language English
format Article
sources DOAJ
author Katja Kemp Jacobsen
Maurice A Lembeck
Sarah Hoffmann
Amalie Wiben
Marie Kruse
Ellen Astrid Holm
spellingShingle Katja Kemp Jacobsen
Maurice A Lembeck
Sarah Hoffmann
Amalie Wiben
Marie Kruse
Ellen Astrid Holm
Predictive validity of PRISMA-7 as a screening instrument for frailty in a hospital setting
BMJ Open
author_facet Katja Kemp Jacobsen
Maurice A Lembeck
Sarah Hoffmann
Amalie Wiben
Marie Kruse
Ellen Astrid Holm
author_sort Katja Kemp Jacobsen
title Predictive validity of PRISMA-7 as a screening instrument for frailty in a hospital setting
title_short Predictive validity of PRISMA-7 as a screening instrument for frailty in a hospital setting
title_full Predictive validity of PRISMA-7 as a screening instrument for frailty in a hospital setting
title_fullStr Predictive validity of PRISMA-7 as a screening instrument for frailty in a hospital setting
title_full_unstemmed Predictive validity of PRISMA-7 as a screening instrument for frailty in a hospital setting
title_sort predictive validity of prisma-7 as a screening instrument for frailty in a hospital setting
publisher BMJ Publishing Group
series BMJ Open
issn 2044-6055
publishDate 2020-10-01
description Objectives Frailty is a major clinical geriatric syndrome associated with serious adverse events including functional disability, falls, hospitalisation, increased morbidity and mortality. The aim of this study was to study the associations between frailty defined as Program of Research to Integrate Services for the Maintenance of Autonomy (PRISMA-7) score ≥3 and use of healthcare resources in hospital and in the municipality as well as association between frailty and mortality.Design Register-based retrospective study.Setting The target population consists of patients aged 75 years or above who, during hospital stay, were assessed by a physiotherapist, and at discharge from hospital were prescribed further physical training in the community.Participants 973 individuals aged 75+ years were included.Outcome measures We examined associations between frailty and use of healthcare resources in hospital and in the municipality as well as the association between frailty and mortality.Results 973 individuals aged 75+ years were included. Of these, 63.9% had a PRISMA-7 score ≥3 and were thus defined as frail. Frail individuals were older compared with non-frail with mean ages of 84.6 and 80.4 years, respectively, p>0.001. Age and gender-adjusted mortality after 1 year was higher among the frail (OR 2.46, 95% CI 1.53 to 3.97). Use of healthcare services in the municipality as well as hospital admissions was significantly higher among frail individuals.Conclusions Based on these findings we consider PRISMA-7 to be useful in an in-hospital setting as a screening tool to identify frail elderly patients who may profit from further geriatric assessment during hospital stay.Trial registration number ID REG-070-2017.
url https://bmjopen.bmj.com/content/10/10/e038768.full
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