Amino acidic substitutions in the polymerase N-terminal region of a reassortant betanodavirus strain causing poor adaptation to temperature increase
Abstract Nervous necrosis virus (NNV), Genus Betanodavirus, is the causative agent of viral encephalopathy and retinopathy (VER), a neuropathological disease that causes fish mortalities worldwide. The NNV genome is composed of two single-stranded RNA molecules, RNA1 and RNA2, encoding the RNA polym...
Main Authors: | Sandra Souto, Lucía Vázquez-Salgado, José G. Olveira, Isabel Bandín |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-06-01
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Series: | Veterinary Research |
Online Access: | http://link.springer.com/article/10.1186/s13567-019-0669-4 |
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