Functional characterization of sticholysin I and W111C mutant reveals the sequence of the actinoporin's pore assembly.

Functional characterization of sticholysin I and W111C mutant reveals the sequence of the actinoporin's pore assembly.

The use of pore-forming toxins in the construction of immunotoxins against tumour cells is an alternative for cancer therapy. In this protein family one of the most potent toxins are the actinoporins, cytolysins from sea anemones. We work on the construction of tumour proteinase-activated immunotoxi...

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Bibliographic Details
Main Authors:	Valeria Antonini, Victor Pérez-Barzaga, Silvia Bampi, David Pentón, Diana Martínez, Mauro Dalla Serra, Mayra Tejuca
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4211696?pdf=render

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