Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss Women
An adequate mineral supply to preterm infants is essential for normal growth and development. This study aimed to compare the mineral contents of human milk (HM) from healthy mothers of preterm (28−32 weeks) and full term (>37 weeks) infants. Samples were collected weekly for eight...
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doaj-acf76213d53f4d6988b3290445a570bf2020-11-25T01:57:17ZengMDPI AGNutrients2072-66432019-08-01118185510.3390/nu11081855nu11081855Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss WomenMagalie Sabatier0Clara L. Garcia-Rodenas1Carlos A. De Castro2Peter Kastenmayer3Mario Vigo4Stéphane Dubascoux5Daniel Andrey6Marine Nicolas7Janique Richoz Payot8Valentine Bordier9Sagar K. Thakkar10Lydie Beauport11Jean-François Tolsa12Céline J. Fischer Fumeaux13Michael Affolter14Nestlé Research, Société des Produits Nestlé SA, 1000 Lausanne, SwitzerlandNestlé Research, Société des Produits Nestlé SA, 1000 Lausanne, SwitzerlandNestle Research Singapore Hub, Société des Produits Nestlé SA, 29 Quality Road, Singapore 618802, SingaporeNestlé Research, Société des Produits Nestlé SA, 1000 Lausanne, SwitzerlandNestlé Research, Société des Produits Nestlé SA, 1000 Lausanne, SwitzerlandNestlé Research, Société des Produits Nestlé SA, 1000 Lausanne, SwitzerlandNestlé Research, Société des Produits Nestlé SA, 1000 Lausanne, SwitzerlandNestlé Research, Société des Produits Nestlé SA, 1000 Lausanne, SwitzerlandNestlé Research, Société des Produits Nestlé SA, 1000 Lausanne, SwitzerlandNestlé Research, Société des Produits Nestlé SA, 1000 Lausanne, SwitzerlandNestle Research Singapore Hub, Société des Produits Nestlé SA, 29 Quality Road, Singapore 618802, SingaporeClinic of Neonatology, Department Woman Mother Child, University Hospital of Lausanne, 1011 Lausanne, SwitzerlandClinic of Neonatology, Department Woman Mother Child, University Hospital of Lausanne, 1011 Lausanne, SwitzerlandClinic of Neonatology, Department Woman Mother Child, University Hospital of Lausanne, 1011 Lausanne, SwitzerlandNestlé Research, Société des Produits Nestlé SA, 1000 Lausanne, SwitzerlandAn adequate mineral supply to preterm infants is essential for normal growth and development. This study aimed to compare the mineral contents of human milk (HM) from healthy mothers of preterm (28−32 weeks) and full term (>37 weeks) infants. Samples were collected weekly for eight weeks for the term group (<i>n</i> = 34) and, biweekly up to 16 weeks for the preterm group (<i>n</i> = 27). Iron, zinc, selenium, copper, iodine, calcium, magnesium, phosphorus, potassium, and sodium were quantitatively analyzed by Inductively Coupled Plasma-Mass Spectrometry. The mineral contents of both HM showed parallel compositional changes over the period of lactation, with occasional significant differences when compared at the same postpartum age. However, when the comparisons were performed at an equivalent postmenstrual age, preterm HM contained less zinc and copper from week 39 to 48 (<i>p</i> < 0.002) and less selenium from week 39 to 44 (<i>p</i> < 0.002) than term HM. This translates into ranges of differences (min−max) of 53% to 78%, 30% to 72%, and 11% to 33% lower for zinc, copper, and selenium, respectively. These data provide comprehensive information on the temporal changes of ten minerals in preterm HM and may help to increase the accuracy of the mineral fortification of milk for preterm consumption.https://www.mdpi.com/2072-6643/11/8/1855human milktermpretermcalciumphosphorusmagnesiumzincironcopperiodineseleniumpotassiumsodium |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Magalie Sabatier Clara L. Garcia-Rodenas Carlos A. De Castro Peter Kastenmayer Mario Vigo Stéphane Dubascoux Daniel Andrey Marine Nicolas Janique Richoz Payot Valentine Bordier Sagar K. Thakkar Lydie Beauport Jean-François Tolsa Céline J. Fischer Fumeaux Michael Affolter |
spellingShingle |
Magalie Sabatier Clara L. Garcia-Rodenas Carlos A. De Castro Peter Kastenmayer Mario Vigo Stéphane Dubascoux Daniel Andrey Marine Nicolas Janique Richoz Payot Valentine Bordier Sagar K. Thakkar Lydie Beauport Jean-François Tolsa Céline J. Fischer Fumeaux Michael Affolter Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss Women Nutrients human milk term preterm calcium phosphorus magnesium zinc iron copper iodine selenium potassium sodium |
author_facet |
Magalie Sabatier Clara L. Garcia-Rodenas Carlos A. De Castro Peter Kastenmayer Mario Vigo Stéphane Dubascoux Daniel Andrey Marine Nicolas Janique Richoz Payot Valentine Bordier Sagar K. Thakkar Lydie Beauport Jean-François Tolsa Céline J. Fischer Fumeaux Michael Affolter |
author_sort |
Magalie Sabatier |
title |
Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss Women |
title_short |
Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss Women |
title_full |
Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss Women |
title_fullStr |
Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss Women |
title_full_unstemmed |
Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss Women |
title_sort |
longitudinal changes of mineral concentrations in preterm and term human milk from lactating swiss women |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2019-08-01 |
description |
An adequate mineral supply to preterm infants is essential for normal growth and development. This study aimed to compare the mineral contents of human milk (HM) from healthy mothers of preterm (28−32 weeks) and full term (>37 weeks) infants. Samples were collected weekly for eight weeks for the term group (<i>n</i> = 34) and, biweekly up to 16 weeks for the preterm group (<i>n</i> = 27). Iron, zinc, selenium, copper, iodine, calcium, magnesium, phosphorus, potassium, and sodium were quantitatively analyzed by Inductively Coupled Plasma-Mass Spectrometry. The mineral contents of both HM showed parallel compositional changes over the period of lactation, with occasional significant differences when compared at the same postpartum age. However, when the comparisons were performed at an equivalent postmenstrual age, preterm HM contained less zinc and copper from week 39 to 48 (<i>p</i> < 0.002) and less selenium from week 39 to 44 (<i>p</i> < 0.002) than term HM. This translates into ranges of differences (min−max) of 53% to 78%, 30% to 72%, and 11% to 33% lower for zinc, copper, and selenium, respectively. These data provide comprehensive information on the temporal changes of ten minerals in preterm HM and may help to increase the accuracy of the mineral fortification of milk for preterm consumption. |
topic |
human milk term preterm calcium phosphorus magnesium zinc iron copper iodine selenium potassium sodium |
url |
https://www.mdpi.com/2072-6643/11/8/1855 |
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