ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery
Anticancer drugs often have widespread effects on the cellular proteome. Here, the authors generate a proteome signature library of drug-treated cancer cell lines and develop a software tool to deconvolute drug targets and gain insights into their mechanisms of action.
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2019-12-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-13582-8 |