Defining the Progression of Diabetic Cardiomyopathy in a Mouse Model of Type 1 Diabetes

Defining the Progression of Diabetic Cardiomyopathy in a Mouse Model of Type 1 Diabetes

The incidence of diabetes and its association with increased cardiovascular disease risk represents a major health issue worldwide. Diabetes-induced hyperglycemia is implicated as a central driver of responses in the diabetic heart such as cardiomyocyte hypertrophy, fibrosis, and oxidative stress, t...

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Bibliographic Details
Main Authors: Miles J. De Blasio, Nguyen Huynh, Minh Deo, Leslie E. Dubrana, Jesse Walsh, Andrew Willis, Darnel Prakoso, Helen Kiriazis, Daniel G. Donner, John C. Chatham, Rebecca H. Ritchie
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Physiology
Subjects:
type 1 diabetes
diabetic cardiomyopathy
cardiomyocyte hypertrophy
cardiac fibrosis
diastolic dysfunction
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00124/full

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