Radical Carbonylative Synthesis of Heterocycles by Visible Light Photoredox Catalysis

Visible light photocatalytic radical carbonylation has been established as a robust tool for the efficient synthesis of carbonyl-containing compounds. Acyl radicals serve as the key intermediates in these useful transformations and can be generated from the addition of alkyl or aryl radicals to carb...

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Main Authors: Xiao-Qiang Hu, Zi-Kui Liu, Wen-Jing Xiao
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Catalysts
Subjects:
Online Access:https://www.mdpi.com/2073-4344/10/9/1054
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spelling doaj-ad221cfe5f184a8ea7b11702518850992020-11-25T03:06:34ZengMDPI AGCatalysts2073-43442020-09-01101054105410.3390/catal10091054Radical Carbonylative Synthesis of Heterocycles by Visible Light Photoredox CatalysisXiao-Qiang Hu0Zi-Kui Liu1Wen-Jing Xiao2Key Laboratory of Catalysis and Energy Materials Chemistry of Ministry of Education & Hubei Key Laboratory of Catalysis and Materials Science, School of Chemistry and Materials Science, South-Central University for Nationalities, Wuhan 430074, ChinaKey Laboratory of Catalysis and Energy Materials Chemistry of Ministry of Education & Hubei Key Laboratory of Catalysis and Materials Science, School of Chemistry and Materials Science, South-Central University for Nationalities, Wuhan 430074, ChinaKey Laboratory of Pesticide & Chemical Biology Ministry of Education, College of Chemistry, Central China Normal University (CCNU), Wuhan 430079, ChinaVisible light photocatalytic radical carbonylation has been established as a robust tool for the efficient synthesis of carbonyl-containing compounds. Acyl radicals serve as the key intermediates in these useful transformations and can be generated from the addition of alkyl or aryl radicals to carbon monoxide (CO) or various acyl radical precursors such as aldehydes, carboxylic acids, anhydrides, acyl chlorides or α-keto acids. In this review, we aim to summarize the impact of visible light-induced acyl radical carbonylation reactions on the synthesis of oxygen and nitrogen heterocycles. The discussion is mainly categorized based on different types of acyl radical precursors.https://www.mdpi.com/2073-4344/10/9/1054radical carbonylationacyl radicalvisible light photocatalysisheterocycles
collection DOAJ
language English
format Article
sources DOAJ
author Xiao-Qiang Hu
Zi-Kui Liu
Wen-Jing Xiao
spellingShingle Xiao-Qiang Hu
Zi-Kui Liu
Wen-Jing Xiao
Radical Carbonylative Synthesis of Heterocycles by Visible Light Photoredox Catalysis
Catalysts
radical carbonylation
acyl radical
visible light photocatalysis
heterocycles
author_facet Xiao-Qiang Hu
Zi-Kui Liu
Wen-Jing Xiao
author_sort Xiao-Qiang Hu
title Radical Carbonylative Synthesis of Heterocycles by Visible Light Photoredox Catalysis
title_short Radical Carbonylative Synthesis of Heterocycles by Visible Light Photoredox Catalysis
title_full Radical Carbonylative Synthesis of Heterocycles by Visible Light Photoredox Catalysis
title_fullStr Radical Carbonylative Synthesis of Heterocycles by Visible Light Photoredox Catalysis
title_full_unstemmed Radical Carbonylative Synthesis of Heterocycles by Visible Light Photoredox Catalysis
title_sort radical carbonylative synthesis of heterocycles by visible light photoredox catalysis
publisher MDPI AG
series Catalysts
issn 2073-4344
publishDate 2020-09-01
description Visible light photocatalytic radical carbonylation has been established as a robust tool for the efficient synthesis of carbonyl-containing compounds. Acyl radicals serve as the key intermediates in these useful transformations and can be generated from the addition of alkyl or aryl radicals to carbon monoxide (CO) or various acyl radical precursors such as aldehydes, carboxylic acids, anhydrides, acyl chlorides or α-keto acids. In this review, we aim to summarize the impact of visible light-induced acyl radical carbonylation reactions on the synthesis of oxygen and nitrogen heterocycles. The discussion is mainly categorized based on different types of acyl radical precursors.
topic radical carbonylation
acyl radical
visible light photocatalysis
heterocycles
url https://www.mdpi.com/2073-4344/10/9/1054
work_keys_str_mv AT xiaoqianghu radicalcarbonylativesynthesisofheterocyclesbyvisiblelightphotoredoxcatalysis
AT zikuiliu radicalcarbonylativesynthesisofheterocyclesbyvisiblelightphotoredoxcatalysis
AT wenjingxiao radicalcarbonylativesynthesisofheterocyclesbyvisiblelightphotoredoxcatalysis
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