Identification of ‘safe harbor’ loci in indica rice genome by harnessing the property of zinc-finger nucleases to induce DNA damage and repair.

Identification of ‘safe harbor’ loci in indica rice genome by harnessing the property of zinc-finger nucleases to induce DNA damage and repair.

Zinc-finger nucleases (ZFNs) have proved to be successful tools for targeted genome manipulation in several organisms. Their main property is the induction of double-strand breaks (DSBs) at specific sites, which are further repaired through homologous recombination (HR) or non-homologous end joining...

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Bibliographic Details
Main Authors: Christian eCantos, Perigio eFransisco, Kurniawan Rudi Trijatmiko, Inez eSlamet-Loedin, Prabhjit Kaur Chadha-Mohanty
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Plant Science
Subjects:
zinc-finger nucleases (ZFNs)
safe harbor loci
rice (Oryza sativa L.)
homologous recombination (HR)
double-strand breaks (DSBs)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00302/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00302/full

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