Purging behaviors relate to impaired subjective sleep quality in female patients with anorexia nervosa: a prospective observational study

• Main Authors: Tokusei Tanahashi, Keisuke Kawai, Keita Tatsushima, Chihiro Saeki, Kunie Wakabayashi, Naho Tamura, Tetsuya Ando, Toshio Ishikawa
• Format: Article
• Language: English
• Published: BMC 2017-08-01
• Series: BioPsychoSocial Medicine
• Subjects: Eating disorders; Binge-eating; Vomiting; Circadian rhythm; Sleep duration; Depression
• Online Access: http://link.springer.com/article/10.1186/s13030-017-0107-7

Abstract Background We examined how purging behaviors relate to subjective sleep quality and sleep patterns and how symptoms of disordered eating behaviors relate to global sleep quality in female patients with anorexia nervosa (AN). Methods Participants were new consecutive female inpatients with a primary diagnosis of AN admitted to the Department of Psychosomatic Medicine at Kohnodai Hospital between June 26 and December 25, 2015. We recorded patients’ habitual eating behaviors, laxative overuse, or uretic misuse, and administered the Japanese versions of the Pittsburgh Sleep Quality Index (PSQI-J) and Center for Epidemiologic Studies Depression Scale. Raw PSQI-J data were used to determine sleep patterns (sleep-onset time, wake-up time, and sleep duration). To examine how purging behaviors related to sleep quality, we compared variables between AN restricting type (ANr) and AN binge-eating/purging type (ANbp). Spearman’s rank correlation analysis was used to examine which potential factors influence global PSQI-J score. Results Participants were 20 patients, of whom 12 had ANbp. Two ANr patients (25%) had global PSQI-J scores greater than 5, compared to 9 ANbp patients (75%; P < 0.05). Circadian rhythm disruption and abnormal sleep duration were significantly greater in ANbp patients than in ANr patients (P < 0.05). Global PSQI-J was significantly correlated with a diagnosis of ANbp (ρ = 0.525; P < 0.05), vomiting (ρ = 0.561; P < 0.05), and duration of illness (ρ = 0.536; P < 0.05). Conclusions ANbp patients had worse global sleep quality and greater disrupted sleep than did ANr patients. This suggests that treatments focusing on sleep would be useful, especially for ANbp patients. Furthermore, vomiting and duration of illness should be considered essential factors related to impaired global sleep quality. Trial registration Not applicable.