Nestin is essential for zebrafish brain and eye development through control of progenitor cell apoptosis.

BACKGROUND: Nestin is expressed in neural progenitor cells (NPC) of developing brain. Despite its wide use as an NPC marker, the function of nestin in embryo development is unclear. METHODOLOGY/PRINCIPAL FINDINGS: As nestin is conserved in zebrafish and its predicted sequence is clustered with the m...

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Bibliographic Details
Main Authors: Hua-Ling Chen, Chiou-Hwa Yuh, Kenneth K Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2824827?pdf=render

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