Trioxolone Methyl, a Novel Cyano Enone-Bearing 18βH-Glycyrrhetinic Acid Derivative, Ameliorates Dextran Sulphate Sodium-Induced Colitis in Mice

Trioxolone Methyl, a Novel Cyano Enone-Bearing 18βH-Glycyrrhetinic Acid Derivative, Ameliorates Dextran Sulphate Sodium-Induced Colitis in Mice

Semi-synthetic triterpenoids, bearing cyano enone functionality in ring A, are considered to be novel promising therapeutic agents with complex inhibitory effects on tissue damage, inflammation and tumor growth. Previously, we showed that the cyano enone-containing 18βH-glycyrrhetinic acid derivativ...

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Bibliographic Details
Main Authors: Andrey V. Markov, Aleksandra V. Sen’kova, Oksana V. Salomatina, Evgeniya B. Logashenko, Dina V. Korchagina, Nariman F. Salakhutdinov, Marina A. Zenkova
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
cyano enone
soloxolone methyl
18βH-glycyrrhetinic acid
CDDO-Me
colitis
inflammation
Online Access:https://www.mdpi.com/1420-3049/25/10/2406

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