The role of neuronal calcium sensors in balancing synaptic plasticity and synaptic dysfunction

The role of neuronal calcium sensors in balancing synaptic plasticity and synaptic dysfunction

Neuronal Calcium Sensors (NCS) readily bind calcium and undergo conformational changes enabling them to interact and regulate specific target molecules. These interactions lead to dynamic alterations in protein trafficking that significantly impact upon synaptic function. Emerging evidence suggests...

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Bibliographic Details
Main Authors: Talitha Lynn Kerrigan, Daniel eWhitcomb, Philip eRegan, Kwangwook eCho
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Alzheimer's disease
Long-term synaptic plasticity
Neuronal Calcium Sensor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00057/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00057/full

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