Curcumin Ameliorates Lead-Induced Hepatotoxicity by Suppressing Oxidative Stress and Inflammation, and Modulating Akt/GSK-3β Signaling Pathway

Curcumin Ameliorates Lead-Induced Hepatotoxicity by Suppressing Oxidative Stress and Inflammation, and Modulating Akt/GSK-3β Signaling Pathway

Lead (Pb) is a toxic heavy metal pollutant with adverse effects on the liver and other body organs. Curcumin (CUR) is the principal curcuminoid of turmeric and possesses strong antioxidant and anti-inflammatory activities. This study explored the protective effect of CUR on Pb hepatotoxicity with an...

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Bibliographic Details
Main Authors: Ahlam Alhusaini, Laila Fadda, Iman H. Hasan, Enas Zakaria, Abeer M. Alenazi, Ayman M. Mahmoud
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Biomolecules
Subjects:
lead
curcumin
gsk-3β
jnk
nf-κb
oxidative stress
Online Access:https://www.mdpi.com/2218-273X/9/11/703

Internet

https://www.mdpi.com/2218-273X/9/11/703

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