Traditional Chinese medicine of Salvia miltiorrhiza Bunge: a review of phytochemistry, pharmacology and pharmacokinetics

Salvia miltiorrhiza Bunge, known as red sage or Danshen, is commonly applied in Chinese herbal therapeutics for various biological effects. In 25–220 C.E., the earliest Chinese Materia Medica referred to as Shengong’s Classic of Materia Medica (Eastern Han Dynasty of China, 200 C.E.) initially docum...

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Bibliographic Details
Main Authors: Ebuka-Olisaemeka Nwafor, Peng Lu, Jia-Wei Li, Qing-Qing Zhang, Dong-Li Qi, Zhi-Dong Liu, Hui Peng, Huan Qin, Yan-Quan Gao, Ji-Lin Wang
Format: Article
Language:English
Published: Hong Kong Gold Orchid Science and Technology Co., Limited 2021-07-01
Series:Traditional Medicine Research
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Online Access:https://www.tmrjournals.com/article.html?J_num=1&a_id=1174
Description
Summary:Salvia miltiorrhiza Bunge, known as red sage or Danshen, is commonly applied in Chinese herbal therapeutics for various biological effects. In 25–220 C.E., the earliest Chinese Materia Medica referred to as Shengong’s Classic of Materia Medica (Eastern Han Dynasty of China, 200 C.E.) initially documented Salvia miltiorrhiza Bunge. Currently, Salvia miltiorrhiza Bunge is one of the most frequently prescribed traditional Chinese medicines in clinics for antidiabetic, antianxiety, antihypertensive, antidepressant, antilipidemic, antiarrhythmic, and anticancer effects. Undoubtedly, it is best known for improving and promoting blood circulation; thus, its recommendation for use in cardiovascular disorders. Regarding this article, important information was sourced both manually and electronically using patent compendium and databases, including Google Scholar, herbal plant monographs, Hindawi, PubMed, Embase, CNKI, pharmacopoeias, Springer, etc. Well-concise details and discussions on the botany, traditional medicinal uses, chemical constituents-phytochemistry, pharmacokinetics, pharmacology, and toxicology information are presented. In perspective, understanding the comprehensive information of the above-stated fields with regards to Salvia miltiorrhiza Bunge would yield an additional positive knowledge on areas that need urgent attention and identify gaps in research and safety for future consideration.
ISSN:2413-3973
2413-3973