Salmonella enterica Serovar Typhi conceals the invasion-associated type three secretion system from the innate immune system by gene regulation.

Delivery of microbial products into the mammalian cell cytosol by bacterial secretion systems is a strong stimulus for triggering pro-inflammatory host responses. Here we show that Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid fever, tightly regulates expression of the...

Full description

Bibliographic Details
Main Authors: Sebastian E Winter, Maria G Winter, Victor Poon, A Marijke Keestra, Torsten Sterzenbach, Franziska Faber, Luciana F Costa, Fabiane Cassou, Erica A Costa, Geraldo E S Alves, Tatiane A Paixão, Renato L Santos, Andreas J Bäumler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4081808?pdf=render