Salmonella enterica Serovar Typhi conceals the invasion-associated type three secretion system from the innate immune system by gene regulation.
Delivery of microbial products into the mammalian cell cytosol by bacterial secretion systems is a strong stimulus for triggering pro-inflammatory host responses. Here we show that Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid fever, tightly regulates expression of the...
Main Authors: | Sebastian E Winter, Maria G Winter, Victor Poon, A Marijke Keestra, Torsten Sterzenbach, Franziska Faber, Luciana F Costa, Fabiane Cassou, Erica A Costa, Geraldo E S Alves, Tatiane A Paixão, Renato L Santos, Andreas J Bäumler |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-07-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4081808?pdf=render |
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