The casein kinase 2 inhibitor, CX-4945, as an anti-cancer drug in treatment of human hematological malignancies

The casein kinase 2 inhibitor, CX-4945, as an anti-cancer drug in treatment of human hematological malignancies

The casein kinase 2 (CK2) protein kinase is a pro-survival kinase and therapeutic target in treatment of various human cancers. CK2 overexpression has been demonstrated in hematological malignancies, including chronic lymphocytic leukemia, chronic myeloid leukemia, acute lymphoblastic leukemia, acut...

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Bibliographic Details
Main Authors: Hae Jung eChon, Kyoung Jun eBae, Yura eLee, Jiyeon eKim
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Pharmacology
Subjects:
ALL
AML
CML
CLL
CK2
CX-4945
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00070/full

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