Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated Genes.

Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated Genes.

Type-I interferon (IFN)-induced activation of the mammalian target of rapamycin (mTOR) signaling pathway has been implicated in translational control of mRNAs encoding interferon-stimulated genes (ISGs). However, mTOR-sensitive translatomes commonly include mRNAs with a 5' terminal oligopyrimid...

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Bibliographic Details
Main Authors: Mark Livingstone, Kristina Sikström, Philippe A Robert, Gilles Uzé, Ola Larsson, Sandra Pellegrini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0133482

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