Anemarrhena asphodeloides Non-Steroidal Saponin Components Alter the Pharmacokinetic Profile of Its Steroidal Saponins in Rat

Anemarrhena asphodeloides Non-Steroidal Saponin Components Alter the Pharmacokinetic Profile of Its Steroidal Saponins in Rat

A rapid, selective and sensitive UPLC-MS/MS assay was established to determine the plasma concentrations of four steroidal saponins. Sprague-Dawley rats were allocated to four groups which were orally administered Anemarrhena asphodeloides extracts (ASE), ASE combined with macromolecular fraction (A...

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Bibliographic Details
Main Authors: Zhishu Tang, Guolong Li, Jie Yang, Jinao Duan, Dawei Qian, Jianming Guo, Zhenhua Zhu, Zhongxing Song
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Molecules
Subjects:
A. asphodeloides extract
steroidal saponins
non-steroidal saponins
UPLC-TQ/MS
pharmacokinetics influence
Online Access:http://www.mdpi.com/1420-3049/20/7/11777

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