Estrategias en el desarrollo de métodos analíticos para la determinación simultánea de compuestos orgánicos por espectrofotometría derivada Strategies used to develop analytical methods for simultaneous determination of organic compounds by derivative spectrophotometry

• Main Authors: M. Inés Toral, Sandra Orellana, Marta Saldías, César Soto
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Química 2009-01-01
• Series: Química Nova
• Subjects: derivative spectrophotometry; losartan; hydrochlorothiazide
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000100043

<abstract language="eng">In this work is proposed, a simple experiment for the simultaneous determination of losartan (L) and hydrochlorothiazide (H) in synthetic and real samples by derivative spectrophotometry technique. For the students it is relevant to know this technique for simultaneous determinations of drugs, allowing that the students recognize that this technique is simple, rapid and applicable to quality control. This experimental work, it is proposed in order to being applied to undergraduates into laboratories of analytical chemistry. Furthermore, it is given the integration of the theoretical knowledge with the experimental work; this correlation is of interest for the students.