Down-Regulation of Brain-Pancreas Relative Protein in Diabetic Rats and by High Glucose in PC12 Cells: Prevention by Calpain Inhibitors
Brain-pancreas relative protein (BPRP) is a novel protein that we found in our laboratory. Previously we demonstrated that it is involved in ischemia and depression. In light of the putative association between diabetes and clinical depression, and the selective expression of BPRP in brain and pancr...
Main Authors: | Lu Tie, Ying Xu, Yan-Hua Lin, Xiao-Hao Yao, Hong-Li Wu, Yu-Hua Li, Zhu-Fang Shen, He-Ming Yu, Xue-Jun Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2008-01-01
|
Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319315336 |
Similar Items
-
Knocking down TRPM2 expression reduces cell injury and NLRP3 inflammasome activation in PC12 cells subjected to oxygen-glucose deprivation
by: Tao Pan, et al.
Published: (2020-01-01) -
Calpain system protein expression in carcinomas of the pancreas, bile duct and ampulla
by: Storr Sarah J, et al.
Published: (2012-11-01) -
Calpain-1 and Calpain-2 in the Brain: New Evidence for a Critical Role of Calpain-2 in Neuronal Death
by: Yubin Wang, et al.
Published: (2020-12-01) -
Metabolic stress response implicated in diabetic retinopathy: The role of calpain, and the therapeutic impact of calpain inhibitor
by: Ahmed Y. Shanab, et al.
Published: (2012-12-01) -
M-Calpain Activation Facilitates Seizure Induced KCC2 Down Regulation
by: Li Wan, et al.
Published: (2018-08-01)