Wolfram (DIDMOAD) syndrome: A Case report

• Main Authors: Abdullah Kürsat Cingü, Yasin Bez, Okan Yapar
• Format: Article
• Language: English
• Published: Dicle University Medical School 2009-01-01
• Series: Dicle Medical Journal
• Subjects: DIDMOAD syndrome; Wolfram syndrome; optic atrophy
• Online Access: http://4181.indexcopernicus.com/fulltxt.php?ICID=893532

A 10 years old boy admitted to Ophthalmology Clinic with the complaint of low vision. His ophthalmologic examination showed decreased visual acuity as counting fingers from 2 meters in both eyes. Biomicroscopic examination of his both eyes was normal. Optic atrophy was apparent in his both eyes on fundoscopic examination. He has been followed with the diagnosis of diabetes mellitus type 1 for the last two years and had nocturnal enuresis. He was diagnosed as Wolfram (DIDMOAD) syndrome based on the results of clinical and laboratory examinations. His medical management has been carried out carefully however he was no longer able to attend his school. His IQ was within normal ranges and he was referred to a school which educates visually disabled children. Wolfram syndrome can easily be diagnosed in outpatient clinics since it does not require a genetic analysis. Physicians should keep in mind this diagnosis during their daily practice and provide the best management to the patient by achieving interdisciplinary co-operation.