Periodontal Regeneration Using Platelet-Derived Growth Factor in Infrabony Defects: A Series of Three Cases

The periodontal researchers and clinicians, in an effort to develop effective regenerative therapies, have sought to understand key events involved in the regeneration of periodontium. Polypeptide growth factors are a class of natural biological mediators which regulate key cellular events in tissue...

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Bibliographic Details
Main Authors: Kaustubh Thakare, M. L. Bhongade, Preeti Charde, Priyanka Jaiswal, Nachiket Shah, Aniruddha Deshpande
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2013/849823
Description
Summary:The periodontal researchers and clinicians, in an effort to develop effective regenerative therapies, have sought to understand key events involved in the regeneration of periodontium. Polypeptide growth factors are a class of natural biological mediators which regulate key cellular events in tissue repair. Platelet-derived growth factor (PDGF) is the most thoroughly studied growth factor in periodontal regeneration. The present case series evaluate the effectiveness of platelet-derived growth factor (rh-PDGF-BB) in combination with beta-tricalcium phosphate (β-TCP) to achieve periodontal regeneration in 3 infrabony defects.
ISSN:2090-6447
2090-6455