Mesenteric Microcystic/Reticular Schwannoma: A Diagnostic Dilemma

Microcystic/reticular schwannoma is a rare variant of schwannoma with a predilection for visceral locations including the gastrointestinal tract. Due to overlapping features with other tumours, unawareness of this tumour type may lead to diagnostic pitfalls. We here report a case of microcystic...

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Bibliographic Details
Main Authors: Sandhya S. Ware, Dilip S. Sarate, Ajay D. Jungare, Vinod K. Sawaitu
Format: Article
Language:English
Published: Krishna Institute of Medical Sciences University 2016-01-01
Series:Journal of Krishna Institute of Medical Sciences University
Subjects:
Online Access:http://www.jkimsu.com/jkimsu-vol5no1/JKIMSU,%20Vol.%205,%20No.%201,%20Jan-March%202016%20Page%20130-133.pdf
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Summary:Microcystic/reticular schwannoma is a rare variant of schwannoma with a predilection for visceral locations including the gastrointestinal tract. Due to overlapping features with other tumours, unawareness of this tumour type may lead to diagnostic pitfalls. We here report a case of microcystic/reticular schwannoma arising in the mesentery of a 25-year-old female. The tumour was incidentally discovered by ultrasonography. An operation was performed and histological examination revealed a capsulated tumour composed of spindle cells with reticular pattern set within a myxoid stroma. Differential diagnoses were Extra Gastrointestinal Stromal Tumour (EGIST) with myxoid change, microcystic/reticular schwannoma, Low-Grade Fibromyxoid Sarcoma (LGFMS) and Aggressive Angiomyxoma (AAM). Immunohistochemically, the tumour cells were positive for S-100 protein which was consistent with a peripheral nerve sheath tumour. Albeit very rare, microcystic/reticular schwannoma should be included in the differential diagnosis of mesenteric tumours. The awareness and the knowledge about this rare tumour are needed to achieve the correct diagnosis.
ISSN:2231-4261
2231-4261