Spontaneous rupture of giant gastric stromal tumor into gastric lumen
<p>Abstract</p> <p>Background</p> <p>Gastrointestinal stromal tumors (GIST) constitute a large majority of mesenchymal tumors of the gastrointestinal (GI) tract, which express the c-kit proto-oncogene protein, a cell membrane receptor with tyrosine kinase activity. GI s...
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doaj-ae4fcaa315ae44afb837a545e885fb9c2020-11-24T21:02:02ZengBMCWorld Journal of Surgical Oncology1477-78192005-02-01311110.1186/1477-7819-3-11Spontaneous rupture of giant gastric stromal tumor into gastric lumenDhar Puneet SNandakumar Raghavan RJohn Anil KSudheer Vayoth OMehta Rajiv MSudhindran SurendranBalakrishnan Vallath<p>Abstract</p> <p>Background</p> <p>Gastrointestinal stromal tumors (GIST) constitute a large majority of mesenchymal tumors of the gastrointestinal (GI) tract, which express the c-kit proto-oncogene protein, a cell membrane receptor with tyrosine kinase activity. GI stromal tumors of the stomach are usually associated with bleeding, abdominal pain or a palpable mass.</p> <p>Case presentation</p> <p>A 75-year-old male presented with upper abdominal pain and palpable mass. Computed tomographic (CT) scan of the abdomen showed a large mass arising in the posterior aspect of fundus, body, and greater curvature of the stomach. Second day after the admission, there was significant reduction in the size of the tumor, clinically as well as radiologically. Endoscopic biopsy showed large bulge in fundus and corpus of the stomach posteriorly with an opening in the posterior part of the corpus, and biopsy from the edge of the opening reveled GIST. Patient underwent curative resection.</p> <p>Conclusion</p> <p>Spontaneous ruptured of giant gastric stromal tumor is very rare presentation of stomach GIST. Thorough clinical examination and timely investigation can diagnose rare complication.</p> http://www.wjso.com/content/3/1/11 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dhar Puneet S Nandakumar Raghavan R John Anil K Sudheer Vayoth O Mehta Rajiv M Sudhindran Surendran Balakrishnan Vallath |
spellingShingle |
Dhar Puneet S Nandakumar Raghavan R John Anil K Sudheer Vayoth O Mehta Rajiv M Sudhindran Surendran Balakrishnan Vallath Spontaneous rupture of giant gastric stromal tumor into gastric lumen World Journal of Surgical Oncology |
author_facet |
Dhar Puneet S Nandakumar Raghavan R John Anil K Sudheer Vayoth O Mehta Rajiv M Sudhindran Surendran Balakrishnan Vallath |
author_sort |
Dhar Puneet S |
title |
Spontaneous rupture of giant gastric stromal tumor into gastric lumen |
title_short |
Spontaneous rupture of giant gastric stromal tumor into gastric lumen |
title_full |
Spontaneous rupture of giant gastric stromal tumor into gastric lumen |
title_fullStr |
Spontaneous rupture of giant gastric stromal tumor into gastric lumen |
title_full_unstemmed |
Spontaneous rupture of giant gastric stromal tumor into gastric lumen |
title_sort |
spontaneous rupture of giant gastric stromal tumor into gastric lumen |
publisher |
BMC |
series |
World Journal of Surgical Oncology |
issn |
1477-7819 |
publishDate |
2005-02-01 |
description |
<p>Abstract</p> <p>Background</p> <p>Gastrointestinal stromal tumors (GIST) constitute a large majority of mesenchymal tumors of the gastrointestinal (GI) tract, which express the c-kit proto-oncogene protein, a cell membrane receptor with tyrosine kinase activity. GI stromal tumors of the stomach are usually associated with bleeding, abdominal pain or a palpable mass.</p> <p>Case presentation</p> <p>A 75-year-old male presented with upper abdominal pain and palpable mass. Computed tomographic (CT) scan of the abdomen showed a large mass arising in the posterior aspect of fundus, body, and greater curvature of the stomach. Second day after the admission, there was significant reduction in the size of the tumor, clinically as well as radiologically. Endoscopic biopsy showed large bulge in fundus and corpus of the stomach posteriorly with an opening in the posterior part of the corpus, and biopsy from the edge of the opening reveled GIST. Patient underwent curative resection.</p> <p>Conclusion</p> <p>Spontaneous ruptured of giant gastric stromal tumor is very rare presentation of stomach GIST. Thorough clinical examination and timely investigation can diagnose rare complication.</p> |
url |
http://www.wjso.com/content/3/1/11 |
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