Therapeutic efficacy of Cinnamomum tamala (Buch.-Ham.) and Aegle marmelos (L.) leaf

• Main Authors: DANDAPAT Sukumar, KUMAR Manoj, SINHA M.P.
• Format: Article
• Language: English
• Published: Romanian Association of Balneology, Editura Balneara 2014-09-01
• Series: Balneo Research Journal
• Subjects: Phytochemical; antioxidant; haemolitic
• Online Access: http://bioclima.ro/Balneo%20(71).pdf

ABSTRACT: Medicinal plants are widely used for therapy of various diseases and disorders due to presence of various bioactive phytochemicals. Among the studied phytochemicals polyphenol content was higher (16.7 ± 0.7 g/100g in C. tamala and 6.7 ± 0.61 g/100g in A. marmelos) and flavonoids content was lower in both plants (1.0 ± 1.01 g/100g and 0.9 ± 0.25 g/100g in C. tamala and A. marmelos respectively). Leaf extract of both plant were effective against S. aureus and P. mirabilis (6-10 mm ZOI and 100% inhibition at 0.25mg-5mg of leaf extracts in agar disk diffusion and broth dilution method respectively) and the leaf extract of both plant possess high antioxidant activity, 0.9% and 0.2% at 5µg/mL concentration 4% and 7% at 100 µg/mL concentration of A. marmelos and C. tamala leaf extracts respectively. Aqueous leaf extract of both the plants did not show cytotoxicity by haemolysis at 0.2 mg/mL-1mg/mL concentration. Key -words: Phytochemical, disease, pathogenic, antioxidant, haemolytic.