Orthostatic and Supine Blood Pressures Are Associated with White Matter Hyperintensities in Parkinson Disease
Background and Purpose: Several reports on the elderly population have suggested that orthostatic hypotension is associated with white matter hyperintensities (WMH); however, little information is available on patients with Parkinson’s disease (PD). Methods: We analyzed the association blood pressur...
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Korean Movement Disorders Society
2013-10-01
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doaj-ae7ccf2399034f04a37b3e40dac29c862020-11-24T22:53:34ZengKorean Movement Disorders SocietyJournal of Movement Disorders2005-940X2093-49392013-10-0162232710.14802/jmd.1300619Orthostatic and Supine Blood Pressures Are Associated with White Matter Hyperintensities in Parkinson DiseaseYoon-Sang OhJoong-Seok KimKwang-Soo LeeBackground and Purpose: Several reports on the elderly population have suggested that orthostatic hypotension is associated with white matter hyperintensities (WMH); however, little information is available on patients with Parkinson’s disease (PD). Methods: We analyzed the association blood pressure profiles during tilt table testing with WMH scores in 117 patients with PD. WMH were rated using the semiquantitative visual rating system proposed by Scheltens et al. Results: The presence of orthostatic hypotension was associated with increasing tendency of WMH score and the blood pressure changes during tilting and supine blood pressure were positively correlated with increasing WMH score. Conclusions: This finding indicates that hemodynamic changes associated with orthostatic hypotension may be associated with white matter changes in patients with PD.http://e-jmd.org/upload/jmd-6-2-23-1.pdfParkinson diseaseWhite matter hyperintensityOrthostatic hypotensionSupine blood pressure |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yoon-Sang Oh Joong-Seok Kim Kwang-Soo Lee |
spellingShingle |
Yoon-Sang Oh Joong-Seok Kim Kwang-Soo Lee Orthostatic and Supine Blood Pressures Are Associated with White Matter Hyperintensities in Parkinson Disease Journal of Movement Disorders Parkinson disease White matter hyperintensity Orthostatic hypotension Supine blood pressure |
author_facet |
Yoon-Sang Oh Joong-Seok Kim Kwang-Soo Lee |
author_sort |
Yoon-Sang Oh |
title |
Orthostatic and Supine Blood Pressures Are Associated with White Matter Hyperintensities in Parkinson Disease |
title_short |
Orthostatic and Supine Blood Pressures Are Associated with White Matter Hyperintensities in Parkinson Disease |
title_full |
Orthostatic and Supine Blood Pressures Are Associated with White Matter Hyperintensities in Parkinson Disease |
title_fullStr |
Orthostatic and Supine Blood Pressures Are Associated with White Matter Hyperintensities in Parkinson Disease |
title_full_unstemmed |
Orthostatic and Supine Blood Pressures Are Associated with White Matter Hyperintensities in Parkinson Disease |
title_sort |
orthostatic and supine blood pressures are associated with white matter hyperintensities in parkinson disease |
publisher |
Korean Movement Disorders Society |
series |
Journal of Movement Disorders |
issn |
2005-940X 2093-4939 |
publishDate |
2013-10-01 |
description |
Background and Purpose: Several reports on the elderly population have suggested that orthostatic hypotension is associated with white matter hyperintensities (WMH); however, little information is available on patients with Parkinson’s disease (PD). Methods: We analyzed the association blood pressure profiles during tilt table testing with WMH scores in 117 patients with PD. WMH were rated using the semiquantitative visual rating system proposed by Scheltens et al. Results: The presence of orthostatic hypotension was associated with increasing tendency of WMH score and the blood pressure changes during tilting and supine blood pressure were positively correlated with increasing WMH score. Conclusions: This finding indicates that hemodynamic changes associated with orthostatic hypotension may be associated with white matter changes in patients with PD. |
topic |
Parkinson disease White matter hyperintensity Orthostatic hypotension Supine blood pressure |
url |
http://e-jmd.org/upload/jmd-6-2-23-1.pdf |
work_keys_str_mv |
AT yoonsangoh orthostaticandsupinebloodpressuresareassociatedwithwhitematterhyperintensitiesinparkinsondisease AT joongseokkim orthostaticandsupinebloodpressuresareassociatedwithwhitematterhyperintensitiesinparkinsondisease AT kwangsoolee orthostaticandsupinebloodpressuresareassociatedwithwhitematterhyperintensitiesinparkinsondisease |
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