Prognostic Gene Signature Identification Using Causal Structure Learning: Applications in Kidney Cancer
Identification of molecular-based signatures is one of the critical steps toward finding therapeutic targets in cancer. In this paper, we propose methods to discover prognostic gene signatures under a causal structure learning framework across the whole genome. The causal structures are represented...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2015-01-01
|
Series: | Cancer Informatics |
Online Access: | https://doi.org/10.4137/CIN.S14873 |