Large scale analysis of phenotype-pathway relationships based on GWAS results.

The widely used pathway-based approach for interpreting Genome Wide Association Studies (GWAS), assumes that since function is executed through the interactions of multiple genes, different perturbations of the same pathway would result in a similar phenotype. This assumption, however, was not syste...

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Bibliographic Details
Main Authors: Aharon Brodie, Oholi Tovia-Brodie, Yanay Ofran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25007247/pdf/?tool=EBI