Frequency domain analysis reveals external periodic fluctuations can generate sustained p53 oscillation.
p53 is a well-known tumor suppressor protein that regulates many pathways, such as ones involved in cell cycle and apoptosis. The p53 levels are known to oscillate without damping after DNA damage, which has been a focus of many recent studies. A negative feedback loop involving p53 and MDM2 has bee...
Main Authors: | Yong-Jun Shin, Brandon Hencey, Steven M Lipkin, Xiling Shen |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3145758?pdf=render |
Similar Items
-
Fluctuations in LC Oscillators
by: O. Ondracek, et al.
Published: (1994-03-01) -
Influence of periodic oscillations and fluctuations of the metal level in the crystallizer on the continuous casting process
by: Smirnov Oleksiy М., et al.
Published: (2018-09-01) -
H-channels affect frequency, power and amplitude fluctuations of neuronal network oscillations
by: Oscar Javier eAvella Gonzalez, et al.
Published: (2015-11-01) -
Period/frequency estimation of a nonlinear oscillator
by: Dan Tian, et al.
Published: (2019-12-01) -
Frequency domain analysis of low-frequency oscillations in electric power systems
by: XUE, SHENG-WEN, et al.
Published: (1986)