The Extent of Inflammatory Cell Infiltrate and Fibrosis in Lungs of Telomere- and Surfactant-Related Familial Pulmonary Fibrosis
Familial pulmonary fibrosis (FPF) is a monogenic disease most commonly involving telomere- (TERT) or surfactant- (SFTP) related mutations. These mutations have been shown to alter lymphocytic inflammatory responses, and FPF biopsies with histological lymphocytic infiltrates have been reported. Recen...
Main Authors: | Aernoud A. van Batenburg, Matthijs F. M. van Oosterhout, Sebastiaan N. Knoppert, Karin M. Kazemier, Joanne J. van der Vis, Jan C. Grutters, Roel Goldschmeding, Coline H. M. van Moorsel |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-09-01
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Series: | Frontiers in Medicine |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2021.736485/full |
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