Dkk-3, a Secreted Wnt Antagonist, Suppresses Tumorigenic Potential and Pulmonary Metastasis in Osteosarcoma

Dkk-3, a Secreted Wnt Antagonist, Suppresses Tumorigenic Potential and Pulmonary Metastasis in Osteosarcoma

Osteosarcoma (OS) is the most common primary bone malignancy with a high propensity for local invasion and distant metastasis. Despite current multidisciplinary treatments, there has not been a drastic change in overall prognosis within the past 2 decades. Dickkopf-3 protein (Dkk-3/REIC) has been kn...

Full description

Bibliographic Details
Main Authors: Carol H. Lin, Yi Guo, Samia Ghaffar, Peter McQueen, Jonathan Pourmorady, Alexander Christ, Kevin Rooney, Tao Ji, Ramez Eskander, Xiaolin Zi, Bang H. Hoang
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/2013/147541

Similar Items

Similar Items