Association of Dietary Acid Load with the Prevalence of Metabolic Syndrome among Participants in Baseline Survey of the Japan Multi-Institutional Collaborative Cohort Study
The association between dietary acid load and metabolic syndrome (MetS) has not been fully investigated. A cross-sectional study was performed on 14,042 men and 14,105 women (aged 35–69 years) who participated in a baseline survey of the Japan Multi-Institutional Collaborative Cohort study. Dietary...
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2020-05-01
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Article |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kokichi Arisawa Sakurako Katsuura-Kamano Hirokazu Uemura Nguyen Van Tien Asahi Hishida Takashi Tamura Yoko Kubo Mineko Tsukamoto Keitaro Tanaka Megumi Hara Toshiro Takezaki Daisaku Nishimoto Teruhide Koyama Etsuko Ozaki Sadao Suzuki Takeshi Nishiyama Kiyonori Kuriki Aya Kadota Naoyuki Takashima Hiroaki Ikezaki Masayuki Murata Isao Oze Keitaro Matsuo Haruo Mikami Yohko Nakamura Kenji Takeuchi Kenji Wakai |
spellingShingle |
Kokichi Arisawa Sakurako Katsuura-Kamano Hirokazu Uemura Nguyen Van Tien Asahi Hishida Takashi Tamura Yoko Kubo Mineko Tsukamoto Keitaro Tanaka Megumi Hara Toshiro Takezaki Daisaku Nishimoto Teruhide Koyama Etsuko Ozaki Sadao Suzuki Takeshi Nishiyama Kiyonori Kuriki Aya Kadota Naoyuki Takashima Hiroaki Ikezaki Masayuki Murata Isao Oze Keitaro Matsuo Haruo Mikami Yohko Nakamura Kenji Takeuchi Kenji Wakai Association of Dietary Acid Load with the Prevalence of Metabolic Syndrome among Participants in Baseline Survey of the Japan Multi-Institutional Collaborative Cohort Study Nutrients dietary acid load metabolic syndrome net endogenous acid production cross-sectional study |
author_facet |
Kokichi Arisawa Sakurako Katsuura-Kamano Hirokazu Uemura Nguyen Van Tien Asahi Hishida Takashi Tamura Yoko Kubo Mineko Tsukamoto Keitaro Tanaka Megumi Hara Toshiro Takezaki Daisaku Nishimoto Teruhide Koyama Etsuko Ozaki Sadao Suzuki Takeshi Nishiyama Kiyonori Kuriki Aya Kadota Naoyuki Takashima Hiroaki Ikezaki Masayuki Murata Isao Oze Keitaro Matsuo Haruo Mikami Yohko Nakamura Kenji Takeuchi Kenji Wakai |
author_sort |
Kokichi Arisawa |
title |
Association of Dietary Acid Load with the Prevalence of Metabolic Syndrome among Participants in Baseline Survey of the Japan Multi-Institutional Collaborative Cohort Study |
title_short |
Association of Dietary Acid Load with the Prevalence of Metabolic Syndrome among Participants in Baseline Survey of the Japan Multi-Institutional Collaborative Cohort Study |
title_full |
Association of Dietary Acid Load with the Prevalence of Metabolic Syndrome among Participants in Baseline Survey of the Japan Multi-Institutional Collaborative Cohort Study |
title_fullStr |
Association of Dietary Acid Load with the Prevalence of Metabolic Syndrome among Participants in Baseline Survey of the Japan Multi-Institutional Collaborative Cohort Study |
title_full_unstemmed |
Association of Dietary Acid Load with the Prevalence of Metabolic Syndrome among Participants in Baseline Survey of the Japan Multi-Institutional Collaborative Cohort Study |
title_sort |
association of dietary acid load with the prevalence of metabolic syndrome among participants in baseline survey of the japan multi-institutional collaborative cohort study |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2020-05-01 |
description |
The association between dietary acid load and metabolic syndrome (MetS) has not been fully investigated. A cross-sectional study was performed on 14,042 men and 14,105 women (aged 35–69 years) who participated in a baseline survey of the Japan Multi-Institutional Collaborative Cohort study. Dietary acid load was assessed using the net-endogenous-acid-production (NEAP) score that is closely correlated with the rate of renal net acid excretion. MetS was diagnosed according to the Joint Interim Statement Criteria of 2009 using body-mass index instead of waist circumference. After adjusting for potential confounders, higher NEAP scores were associated with a significantly increased odds ratio (OR) of MetS, obesity, high blood pressure, and high fasting blood glucose. These associations remained significant after further adjustment for carbohydrate intake or two nutrient-pattern scores significantly associated with MetS. After adjustment for fiber, iron, potassium, and vitamin pattern scores, the OR of MetS for the highest quartile of NEAP scores, relative to the lowest quartile, was 1.25 (95% confidence interval 1.12–1.39). There was no significant interaction between sex, age, or body-mass index and NEAP. Higher dietary acid load was associated with a higher prevalence of MetS and several of its components, independently of carbohydrate intake or nutrient patterns. |
topic |
dietary acid load metabolic syndrome net endogenous acid production cross-sectional study |
url |
https://www.mdpi.com/2072-6643/12/6/1605 |
work_keys_str_mv |
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doaj-aeb98b69d3154caea108d2eab53aea652020-11-25T02:39:55ZengMDPI AGNutrients2072-66432020-05-01121605160510.3390/nu12061605Association of Dietary Acid Load with the Prevalence of Metabolic Syndrome among Participants in Baseline Survey of the Japan Multi-Institutional Collaborative Cohort StudyKokichi Arisawa0Sakurako Katsuura-Kamano1Hirokazu Uemura2Nguyen Van Tien3Asahi Hishida4Takashi Tamura5Yoko Kubo6Mineko Tsukamoto7Keitaro Tanaka8Megumi Hara9Toshiro Takezaki10Daisaku Nishimoto11Teruhide Koyama12Etsuko Ozaki13Sadao Suzuki14Takeshi Nishiyama15Kiyonori Kuriki16Aya Kadota17Naoyuki Takashima18Hiroaki Ikezaki19Masayuki Murata20Isao Oze21Keitaro Matsuo22Haruo Mikami23Yohko Nakamura24Kenji Takeuchi25Kenji Wakai26Department of Preventive Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8503, JapanDepartment of Preventive Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8503, JapanDepartment of Preventive Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8503, JapanDepartment of Preventive Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8503, JapanDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Preventive Medicine, Faculty of Medicine, Saga University, Saga 849-8501, JapanDepartment of Preventive Medicine, Faculty of Medicine, Saga University, Saga 849-8501, JapanDepartment of International Island and Community Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, JapanSchool of Health Sciences, Faculty of Medicine, Kagoshima University, Kagoshima 890-8544, JapanDepartment of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Kyoto 602-8566, JapanDepartment of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Kyoto 602-8566, JapanDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, JapanDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, JapanLaboratory of Public Health, Division of Nutritional Sciences, School of Food and Nutritional Sciences, University of Shizuoka, Shizuoka 422-8526, JapanDepartment of Public Health, Shiga University of Medical Science, Otsu, Shiga 520-2192, JapanDepartment of Public Health, Shiga University of Medical Science, Otsu, Shiga 520-2192, JapanDepartment of Comprehensive General Internal Medicine, Faculty of Medical Sciences, Kyushu University Graduate School of Medicine, Fukuoka 812-8582, JapanDepartment of General Internal Medicine, Kyushu University Hospital, Fukuoka 812-8582, JapanDivision of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya 464-8681, JapanDivision of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya 464-8681, JapanCancer Prevention Center, Chiba Cancer Center Research Institute, Chiba 260-8717, JapanCancer Prevention Center, Chiba Cancer Center Research Institute, Chiba 260-8717, JapanDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanThe association between dietary acid load and metabolic syndrome (MetS) has not been fully investigated. A cross-sectional study was performed on 14,042 men and 14,105 women (aged 35–69 years) who participated in a baseline survey of the Japan Multi-Institutional Collaborative Cohort study. Dietary acid load was assessed using the net-endogenous-acid-production (NEAP) score that is closely correlated with the rate of renal net acid excretion. MetS was diagnosed according to the Joint Interim Statement Criteria of 2009 using body-mass index instead of waist circumference. After adjusting for potential confounders, higher NEAP scores were associated with a significantly increased odds ratio (OR) of MetS, obesity, high blood pressure, and high fasting blood glucose. These associations remained significant after further adjustment for carbohydrate intake or two nutrient-pattern scores significantly associated with MetS. After adjustment for fiber, iron, potassium, and vitamin pattern scores, the OR of MetS for the highest quartile of NEAP scores, relative to the lowest quartile, was 1.25 (95% confidence interval 1.12–1.39). There was no significant interaction between sex, age, or body-mass index and NEAP. Higher dietary acid load was associated with a higher prevalence of MetS and several of its components, independently of carbohydrate intake or nutrient patterns.https://www.mdpi.com/2072-6643/12/6/1605dietary acid loadmetabolic syndromenet endogenous acid productioncross-sectional study |