Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report

Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report

Posterior reversible encephalopathy syndrome (PRES) is a newly described adverse effect possibly associated with gonadotropin-releasing hormone (GnRH) agonist therapy. We report a case of PRES after 2 doses of depot GnRH agonists in a 44-year-old woman with a huge myoma uteri and iron-deficiency ane...

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Bibliographic Details
Main Authors: Minhee Lee, Tae Hee Kim, Se Jeong Kim, Byung Chul Jee
Format: Article
Language:English
Published: Korean Society of Obstetrics and Gynecology 2019-01-01
Series:Obstetrics & Gynecology Science
Subjects:
gonadotropin-releasing hormone
leuprolide
brain diseases
myoma
Online Access:http://ogscience.org/upload/pdf/ogs-62-69.pdf
Description
Summary:Posterior reversible encephalopathy syndrome (PRES) is a newly described adverse effect possibly associated with gonadotropin-releasing hormone (GnRH) agonist therapy. We report a case of PRES after 2 doses of depot GnRH agonists in a 44-year-old woman with a huge myoma uteri and iron-deficiency anemia. Brain magnetic resonance imaging showed high signal lesions in both occipital lobes on fluid-attenuated inversion-recovery (FLAIR) images, compatible with PRES. After treatment with anticonvulsant, she recovered both radiographically and clinically. The association between PRES and GnRH agonist use is still enigmatic, and thus should be further clarified.
ISSN:2287-8572
2287-8580

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