Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report

Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report

Posterior reversible encephalopathy syndrome (PRES) is a newly described adverse effect possibly associated with gonadotropin-releasing hormone (GnRH) agonist therapy. We report a case of PRES after 2 doses of depot GnRH agonists in a 44-year-old woman with a huge myoma uteri and iron-deficiency ane...

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Main Authors: Minhee Lee, Tae Hee Kim, Se Jeong Kim, Byung Chul Jee
Format: Article
Language:English
Published: Korean Society of Obstetrics and Gynecology 2019-01-01
Series:Obstetrics & Gynecology Science
Subjects:
gonadotropin-releasing hormone
leuprolide
brain diseases
myoma
Online Access:http://ogscience.org/upload/pdf/ogs-62-69.pdf
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spelling doaj-aec983ee10904486b96901f4e6eb9fba2020-11-25T03:52:33ZengKorean Society of Obstetrics and GynecologyObstetrics & Gynecology Science2287-85722287-85802019-01-01621697210.5468/ogs.2019.62.1.69622Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case reportMinhee Lee0Tae Hee Kim1Se Jeong Kim2Byung Chul Jee3Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, .KoreaDepartment of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, .KoreaDepartment of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, .KoreaDepartment of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, .KoreaPosterior reversible encephalopathy syndrome (PRES) is a newly described adverse effect possibly associated with gonadotropin-releasing hormone (GnRH) agonist therapy. We report a case of PRES after 2 doses of depot GnRH agonists in a 44-year-old woman with a huge myoma uteri and iron-deficiency anemia. Brain magnetic resonance imaging showed high signal lesions in both occipital lobes on fluid-attenuated inversion-recovery (FLAIR) images, compatible with PRES. After treatment with anticonvulsant, she recovered both radiographically and clinically. The association between PRES and GnRH agonist use is still enigmatic, and thus should be further clarified.http://ogscience.org/upload/pdf/ogs-62-69.pdfgonadotropin-releasing hormoneleuprolidebrain diseasesmyoma
collection DOAJ
language English
format Article
sources DOAJ
author Minhee Lee
Tae Hee Kim
Se Jeong Kim
Byung Chul Jee
spellingShingle Minhee Lee
Tae Hee Kim
Se Jeong Kim
Byung Chul Jee
Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
Obstetrics & Gynecology Science
gonadotropin-releasing hormone
leuprolide
brain diseases
myoma
author_facet Minhee Lee
Tae Hee Kim
Se Jeong Kim
Byung Chul Jee
author_sort Minhee Lee
title Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
title_short Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
title_full Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
title_fullStr Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
title_full_unstemmed Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
title_sort posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report
publisher Korean Society of Obstetrics and Gynecology
series Obstetrics & Gynecology Science
issn 2287-8572
2287-8580
publishDate 2019-01-01
description Posterior reversible encephalopathy syndrome (PRES) is a newly described adverse effect possibly associated with gonadotropin-releasing hormone (GnRH) agonist therapy. We report a case of PRES after 2 doses of depot GnRH agonists in a 44-year-old woman with a huge myoma uteri and iron-deficiency anemia. Brain magnetic resonance imaging showed high signal lesions in both occipital lobes on fluid-attenuated inversion-recovery (FLAIR) images, compatible with PRES. After treatment with anticonvulsant, she recovered both radiographically and clinically. The association between PRES and GnRH agonist use is still enigmatic, and thus should be further clarified.
topic gonadotropin-releasing hormone
leuprolide
brain diseases
myoma
url http://ogscience.org/upload/pdf/ogs-62-69.pdf
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AT taeheekim posteriorreversibleencephalopathysyndromeinawomanwhousedgonadotropinreleasinghormoneagonistsacasereport
AT sejeongkim posteriorreversibleencephalopathysyndromeinawomanwhousedgonadotropinreleasinghormoneagonistsacasereport
AT byungchuljee posteriorreversibleencephalopathysyndromeinawomanwhousedgonadotropinreleasinghormoneagonistsacasereport
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