Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans

Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans

We assessed Zika virus RNA and select cytokine levels in semen, blood, and plasma samples from an infected patient in South America. Viral RNA was detected in semen >2 months after viremia clearance; cytokine profiles differed in semen and plasma. After viremia, Zika virus appears to become compa...

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Main Authors: Jean-Michel Mansuy, Hicham El Costa, Jordi Gouilly, Catherine Mengelle, Christophe Pasquier, Guillaume Martin-Blondel, Jacques Izopet, Nabila Jabrane-Ferrat
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2019-04-01
Series:Emerging Infectious Diseases
Subjects:
Zika
Zika virus
cytokines
semen
blood
inflammation
Online Access:https://wwwnc.cdc.gov/eid/article/25/4/17-1886_article
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spelling doaj-aed42aa49f534634b55d6fc77fe404942020-11-25T01:04:25ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592019-04-0125482382510.3201/eid2504.171886Peripheral Plasma and Semen Cytokine Response to Zika Virus in HumansJean-Michel MansuyHicham El CostaJordi GouillyCatherine MengelleChristophe PasquierGuillaume Martin-BlondelJacques IzopetNabila Jabrane-FerratWe assessed Zika virus RNA and select cytokine levels in semen, blood, and plasma samples from an infected patient in South America. Viral RNA was detected in semen >2 months after viremia clearance; cytokine profiles differed in semen and plasma. After viremia, Zika virus appears to become compartmentalized in the male reproductive tract.https://wwwnc.cdc.gov/eid/article/25/4/17-1886_articleZikaZika viruscytokinessemenbloodinflammation
collection DOAJ
language English
format Article
sources DOAJ
author Jean-Michel Mansuy
Hicham El Costa
Jordi Gouilly
Catherine Mengelle
Christophe Pasquier
Guillaume Martin-Blondel
Jacques Izopet
Nabila Jabrane-Ferrat
spellingShingle Jean-Michel Mansuy
Hicham El Costa
Jordi Gouilly
Catherine Mengelle
Christophe Pasquier
Guillaume Martin-Blondel
Jacques Izopet
Nabila Jabrane-Ferrat
Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans
Emerging Infectious Diseases
Zika
Zika virus
cytokines
semen
blood
inflammation
author_facet Jean-Michel Mansuy
Hicham El Costa
Jordi Gouilly
Catherine Mengelle
Christophe Pasquier
Guillaume Martin-Blondel
Jacques Izopet
Nabila Jabrane-Ferrat
author_sort Jean-Michel Mansuy
title Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans
title_short Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans
title_full Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans
title_fullStr Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans
title_full_unstemmed Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans
title_sort peripheral plasma and semen cytokine response to zika virus in humans
publisher Centers for Disease Control and Prevention
series Emerging Infectious Diseases
issn 1080-6040
1080-6059
publishDate 2019-04-01
description We assessed Zika virus RNA and select cytokine levels in semen, blood, and plasma samples from an infected patient in South America. Viral RNA was detected in semen >2 months after viremia clearance; cytokine profiles differed in semen and plasma. After viremia, Zika virus appears to become compartmentalized in the male reproductive tract.
topic Zika
Zika virus
cytokines
semen
blood
inflammation
url https://wwwnc.cdc.gov/eid/article/25/4/17-1886_article
work_keys_str_mv AT jeanmichelmansuy peripheralplasmaandsemencytokineresponsetozikavirusinhumans
AT hichamelcosta peripheralplasmaandsemencytokineresponsetozikavirusinhumans
AT jordigouilly peripheralplasmaandsemencytokineresponsetozikavirusinhumans
AT catherinemengelle peripheralplasmaandsemencytokineresponsetozikavirusinhumans
AT christophepasquier peripheralplasmaandsemencytokineresponsetozikavirusinhumans
AT guillaumemartinblondel peripheralplasmaandsemencytokineresponsetozikavirusinhumans
AT jacquesizopet peripheralplasmaandsemencytokineresponsetozikavirusinhumans
AT nabilajabraneferrat peripheralplasmaandsemencytokineresponsetozikavirusinhumans
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