New 2-Oxoindolin Phosphonates as Novel Agents to Treat Cancer: A Green Synthesis and Molecular Modeling

New 2-Oxoindolin Phosphonates as Novel Agents to Treat Cancer: A Green Synthesis and Molecular Modeling

The work reports the facile synthesis of novel α-aminophosphonate derivatives coupled with indole-2,3-dione moieties, namely the diethyl(substituted phenyl/heteroaryl)(2-(2-oxoindolin-3-ylidene)hydrazinyl)methylphosphonates derivatives 4(a–n). One-pot three component Kabachnik-Fi...

Full description

Bibliographic Details
Main Authors:	Shailee V. Tiwari, Nawaz S. Sharif, Rekha I. Gajare, Julio A. Seijas Vazquez, Jaiprakash N. Sangshetti, Manoj D. Damale, Anna Pratima G. Nikalje
Format:	Article
Language:	English
Published:	MDPI AG 2018-08-01
Series:	Molecules
Subjects:	indole-2,3-dione α-aminophosphonates in-vitro anticancer activity ceric ammonium nitrate docking
Online Access:	http://www.mdpi.com/1420-3049/23/8/1981

Similar Items

Cerium(IV) as Ceric Triethylammonium Nitrate: An Efficient Catalyst for Protection and Deprotection of Alcohols with Dihydropyran
by: Nasser Iranpoor, et al.
Published: (1996-06-01)

Ceric ammonium nitrate and manganese(III) acetate mediated radical oxidation and addition reactions of anthracene and 9-substituted anthracenes
by: Mustafa Zengin, et al.
Published: (2012-06-01)

Optimization of Conditions for the Synthesis and Oxidation of 5,8-Dimethoxy-2-methyl-3,4-dihydroisoquinolin-1(2H)-one into Novel 2-Methylisoquinoline-1,5,8(2H)-trione
by: Basharat Ali, et al.
Published: (2020-05-01)

Synthesis of Novel N-(4-Ethoxyphenyl) Azetidin-2-ones and Their Oxidative N-Deprotection by Ceric Ammonium Nitrate
by: Maaroof Zarei, et al.
Published: (2007-10-01)

Determination of Plutonium Present in Highly Radioactive Irradiated Fuel Solution by Spectrophotometric Method
by: Krishnan Dhamodharan, et al.
Published: (2016-06-01)

Kinetic Study of Graft Polymerization of Acrylic Acid and Ethyl Methacrylate onto Starch by Ceric Ammonium Nitrate
by: Mohammad Taghi Taghizadeh, et al.
Published: (2006-03-01)

<b>Synthesis of 2,3-unsaturated furanic hex- and pent-enopyranoside employing the ferrier rearrangement</b>
by: Soro Yaya, et al.
Published: (2005-12-01)

Efficient carbon-Ferrier rearrangement on glycals mediated by ceric ammonium nitrate: Application to the synthesis of 2-deoxy-2-amino-C-glycoside
by: Alafia A. Ansari, et al.
Published: (2014-01-01)

One-Step Synthesis of Dicyano Imidazoles by (NH4)2Ce(NO3)6/HNO3 Promoted Oxidative Cyclocondensation of an Aldehyde and 2,3-diaminomaleonitrile
by: Mehdi Kalhor, et al.
Published: (2020-12-01)

Ionic Liquid-Catalyzed Green Protocol for Multi-Component Synthesis of Dihydropyrano[2,3-c]pyrazoles as Potential Anticancer Scaffolds
by: Urja D. Nimbalkar, et al.
Published: (2017-09-01)

Synthèses sélectives d’isoxazolines et isoxazoles phosphonates : compétition de C- vs. O-alkylation et cycloadditions d’ynamido-phosphonates
by: Perez, Vincent
Published: (2017)

2-(5-Fluoro-1-methyl-2-oxoindolin-3-ylidene)-N-[4-(methylsulfanyl)phenyl]hydrazine-1-carbothioamide
by: Zeliha Atioğlu, et al.
Published: (2017-05-01)

One-Pot Three-Component Synthesis of Novel Diethyl((2-oxo-1,2-dihydroquinolin-3-yl)(arylamino)methyl)phosphonate as Potential Anticancer Agents
by: Yi-Lin Fang, et al.
Published: (2016-04-01)

Green approach for synthesis of bioactive Hantzsch 1,4-dihydropyridine derivatives based on thiophene moiety via multicomponent reaction
by: M. G. Sharma, et al.
Published: (2017-01-01)

Synthesis and evaluation of anti-inflammatory, antioxidant and antimicrobial activities of densely functionalized novel benzo [d] imidazolyl tetrahydropyridine carboxylates
by: Anisetti Ravindernath, et al.
Published: (2017-02-01)

A study of doped ceria electrolytes
by: Ralph, James Michael
Published: (1998)

Direct Synthesis of Phosphonates and α-Amino-phosphonates from 1,3-Benzoxazines
by: Oscar Salgado-Escobar, et al.
Published: (2019-01-01)

α-(Imino)pyridyldifluoroethyl Phosphonates: Novel Promising Building Blocks in Synthesis of Biorelevant Aminophosphonic Acids Derivatives
by: Oksana M. Shavrina, et al.
Published: (2021-04-01)

A STUDY ON GAMMA RADIATION RESPONSE OF CERIC SULFATE DOSIMETER
by: Shamoon Al Islam, et al.
Published: (2019-01-01)

Sensitive spectrophotometric methods for determination of some organophosphorus pesticides in vegetable samples
by: MAGDA A. AKL, et al.
Published: (2010-03-01)

Rapid Synthesis and Antiviral Activity of (Quinazolin-4-Ylamino)Methyl-Phosphonates Through Microwave Irradiation
by: Baoan Song, et al.
Published: (2012-06-01)

In vitro antitumour activity, safety testing and subcellular distribution of two poly[oxyethylene(aminophosphonate-co-H-phosphonate)]s in Ehrlich ascites carcinoma and BALB/c 3T3 cell culture systems
by: Ani Georgieva, et al.
Published: (2016-01-01)

Synthesis of fluorescent (benzyloxycarbonylamino)(aryl)methylphosphonates
by: Michał Górny vel Górniak, et al.
Published: (2014-03-01)

Crystal structure of diethyl [(4-nitrophenylamino)(2-hydroxyphenyl)methyl]phosphonate methanol monosolvate
by: QingMing Wang, et al.
Published: (2014-09-01)

Suggestions on converting ammonium nitrate manufacturing capacity for production of porous ammonium nitrates and ammonium nitrate with fillers
by: A. L. Taran, et al.
Published: (2009-12-01)

Réactivité des alpha-amino allénylphosphonates : des amino vinylphosphonates aux spirodiénones lactames
by: Adler, Pauline
Published: (2016)

6-(4-Amino-1-methyl-2-(methylthio)-6-oxo-1,6-dihydro-pyrimidin-5-yl)-3,6-dimethyl-2-(methylthio)-6,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-4,5-dione
by: Pablo E. Romo, et al.
Published: (2015-02-01)

Antioxidant and anticancer activities of α-aminophosphonates containing thiadiazole moiety
by: Mohamed M. Azaam, et al.
Published: (2018-01-01)

Short-term interaction between nitrate and ammonium uptake for cells of a marine diatom grown under different degrees of light limitation
by: Yin, Kedong
Published: (2010)

Stereoselective sodium borohydride reductions of cyclopentanones: influence of ceric chloride on the stereochemistry of reaction
by: Constantino Mauricio Gomes, et al.
Published: (1998-01-01)

Phosphonic Acid Analogues of Phenylglycine as Inhibitors of Aminopeptidases: Comparison of Porcine Aminopeptidase N, Bovine Leucine Aminopeptidase, Tomato Acidic Leucine Aminopeptidase and Aminopeptidase from Barley Seeds
by: Weronika Wanat, et al.
Published: (2019-09-01)

CHANGES IN NITROGEN FERTILIZERS MARKET IN POLAND IN 2000-2010
by: Arkadiusz Zalewski
Published: (2013-12-01)

FACTORS AFFECTING GROUND WATER POLLUTION IN THE MEADOW OF BORCEA ARM
by: Cecilia NEAGU
Published: (2014-04-01)

Asymmetric Synthesis of Tetrasubstituted α-Aminophosphonic Acid Derivatives
by: Aitor Maestro, et al.
Published: (2021-05-01)

Enantioselective addition of diphenyl phosphonate to ketimines derived from isatins catalyzed by binaphthyl-modified organocatalysts
by: Hee Seung Jang, et al.
Published: (2016-07-01)

Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine
by: Lin-Hong Jin, et al.
Published: (2003-01-01)

Phosphonate inhibitors of West Nile virus NS2B/NS3 protease
by: Marcin Skoreński, et al.
Published: (2019-01-01)

NH-Polyfluoroalkyl іminophosphonates in the synthesis of α-amino-α-polyfluoroalkyl-γ-oxobutylphosphonic acids
by: O. V. Stanko, et al.
Published: (2019-05-01)

N,N',N"-Tris[(5-methoxy-1H-indol-3-yl)ethyl]benzene-1,3,5-tricarboxamide
by: Ute Schmidt, et al.
Published: (2015-03-01)

Discovery of indole-3-butyric acid derivatives as potent histone deacetylase inhibitors
by: Yiming Chen, et al.
Published: (2021-01-01)

Cannot write session to /tmp/vufind_sessions/sess_808h941k75hlgs9fpoe6j6eo5q