Using joint models to disentangle intervention effect types and baseline confounding: an application within an intervention study in prodromal Alzheimer’s disease with Fortasyn Connect
Abstract Background Many prodromal Alzheimer’s disease trials collect two types of data: the time until clinical diagnosis of dementia and longitudinal patient information. These data are often analysed separately, although they are strongly associated. By combining the longitudinal and survival dat...
Main Authors: | Floor M. van Oudenhoven, Sophie H.N. Swinkels, Tobias Hartmann, Hilkka Soininen, Anneke M.J. van Hees, Dimitris Rizopoulos |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12874-019-0791-z |
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