Transcriptomic Analysis of Age-Associated Periventricular Lesions Reveals Dysregulation of the Immune Response

Transcriptomic Analysis of Age-Associated Periventricular Lesions Reveals Dysregulation of the Immune Response

White matter lesions (WML) are a common feature of the ageing brain associated with cognitive impairment. The gene expression profiles of periventricular lesions (PVL, <i>n</i> = 7) and radiologically-normal-appearing (control) periventricular white matter cases (<i>n</i> = 1...

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Bibliographic Details
Main Authors: Motaz M. Fadul, Paul R. Heath, Johnathan Cooper-Knock, Julian M. Kurz, Hayder A. Al-Azzawi, Zarki Ali, Taylor Smith, Fiona E. Matthews, Carol Brayne, Stephen B. Wharton, Julie E. Simpson
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
periventricular lesions
transcriptomic profiling
nanostring
immune response
Online Access:https://www.mdpi.com/1422-0067/21/21/7924

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